Vice President Al Gore

Fierce lobbying of Congress in 1999 to fight against an ill advised Clinton Administration campaign, which was being led by Vice President Al Gore, to change regulations of the Environmental Protection Agency governing the U.S. chemical industry. 
The Vice President wanted thousand of already tested and already approved chemicals to be re-tested, using millions of live animals in very painful, fatal, poisoning tests.
The lobbying went on for years, and was ultimately successful.